Pharmaceutical Care Berpengaruh terhadap Kualitas Hidup, Kepatuhan dan Outcome Klinis Pasien Diabetes Melitus Tipe 2 di Beberapa Daerah di Indonesia: Kajian Literatur
Keywords:
Compliance, Clinical Outcome, Diabetes Melitus, Quality of Life.
Abstract
Diabetes mellitus is a metabolic disease in which there are abnormalities in insulin secretion, insulin action or both, causing hyperglycemia. Maximizing pharmaceutical services can be done as a step to improve the quality of life of diabetes mellitus patients and this can be done through pharmaceutical care by pharmacists. This literature review aims to determine the best interventions that can improve the quality of life, compliance and clinical outcomes of diabetes mellitus patients. This paper is the result of a literature review of various studies that examined the effect of pharmaceutical care on the quality of life, compliance and clinical outcomes of type 2 diabetes mellitus patients. A literature search was carried out via the Pubmed and Google Scholar websites using the keywords "pharmaceutical care", "patient quality of life diabetes mellitus", "compliance of type 2 diabetes mellitus patients" "clinical outcomes of type 2 diabetes mellitus patients", "the influence of pharmaceutical care on the quality of life of type 2 diabetes mellitus patients", "the influence of pharmaceutical care on the compliance of type 2 diabetes mellitus patients" "the influence pharmaceutical care on the clinical outcomes of type 2 diabetes mellitus patients" from 2015 to 2023. In this research, 13 research studies were found that were related to the research objectives. The results of the literature review show that counseling, education, Drug Information Services (PIO), telefarma and SMS reminders are the best interventions that can improve compliance, clinical outcomes and quality of life for type 2 diabetes mellitus patients.
References
Andanalusia, M., Nita, Y., & Athiyah, U. (2021). The effect of pillbox use and education by pharmacist toward medication adherence in diabetes mellitus patients in a Primary Health Care Center in Mataram. Journal of Basic and Clinical Physiology and Pharmacology, 32(4), 577–582. https://doi.org/10.1515/jbcpp-2020-0500
Ariyani, H., Rahmani, & Hendera. (2022). Pengaruh Konseling Singkat Melalui Telepon Terhadap Penurunan Kadar Gula Darah Pasien Diabetes Melitus Di Puskesmas Alalak Selatan Kota Banjarmasin Utara. JCPS (Journal of Current Pharmaceutical Sciences), 5(2), 508–513.
Basuki, E. S. (2009). Konseling Medik : Kunci Menuju Kepatuhan Pasien. Majalah Kedokteran Indonesia, 59, 55–60.
Besemah, N. A., Sartika, R. A. D., & Sauriasari, R. (2021). Effect of Pharmacist Intervention on Medication Adherence and Clinical Outcomes of Type 2 Diabetes Mellitus Outpatients in Primary Healthcare in Indonesia. Journal of Research in Pharmacy Practice, 9(4), 186–195. https://doi.org/10.4103/jrpp.JRPP_20_59
Departemen Kesehatan Republik Indonesia. (2008). Riset Kesehatan Dasar 2007. In Laporan Nasional 2007. http://kesga.kemkes.go.id/images/pedoman/Riskesdas 2007 Nasional.pdf
Fajriansyah, Iskandarsyah, A., Puspitasari, I. M., & Lestari, K. (2020). Impact of pharmacist counseling on health-related quality of life of patients with type 2 diabetes mellitus: a cluster randomized controlled study. Journal of Diabetes and Metabolic Disorders, 19(2), 675–682. https://doi.org/10.1007/s40200-020-00528-x
Fitriana, Z., & Salviana, E. A. (2021). Analisis Faktor yang Mempengaruhi Kepatuhan Menjalankan Diet Pada Lansia Penderita Diabetes Melitus Tipe Dua. Jurnal Keperawatan Silampari, 4(2), 351–358.
Jannah, F., Safutra Suraya, A., Erindia, F., Nurwahidah, N., & Chayatush Sholichah, A. (2023). The Benefits of Telehealth on Quality of Life of People Living with Type 2 Diabetes Mellitus: A Literature Review. Fundamental and Management Nursing Journal, 6(2), 69–77. https://doi.org/10.20473/fmnj.v6i2.48692
Kementrian kesehatan republik indonesia. (2020). Tetap Produktif, Cegah Dan Atasi Diabetes Mellitus. In Pusat data dan informasi kementrian kesehatan RI.
Khairunnisa, Rawitri, K., Wiryanto, & Wahyuni, S. (2021). Pengaruh Asuhan Kefarmasian Terhadap Outcome Klinis Dan Kualitas Hidup Pada Pasien Diabetes Melitus Tipe 2. Jurnal Farmasi Indonesia, 13(2), 118–128. https://doi.org/10.35617/jfionline.v13i2.18
Laxmi, D., Kumala, S., Sarnianto, P., & Tarigan, A. (2021). Pengaruh Edukasi Farmasis Terhadap Hasil Terapi dan Kualitas Hidup Pasien Prolanis Diabetes Melitus Tipe 2. Jurnal Ilmiah Indonesia, 6(1), 154–172. http://www.nber.org/papers/w16019
Mayasari, Y., Sarnianto, P., & Anggraini, Y. (2020). Pengaruh Asuhan Kefarmasian Terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Dua Puskesmas Daerah Jakarta Timur. Jurnal Ilmiah Indonesia, 5(6), 221–232.
Octaviani, P. (2017). Pengaruh Pemberian Konseling Farmasis dengan Alat Bantu Terhadap Kepatuhan Pasien Diabetes Melitus Tipe 2 Anggota Prolanis di Puskesmas Purwokerto Utara. Viva Medika, 10(1), 68–78.
Partika, R., Angraini, D. I., & Fakhruddin, H. (2018). Pengaruh Konseling Gizi Dokter terhadap Peningkatan Kepatuhan Diet Pasien Diabetes Melitus Tipe 2. Majority, 7(3), 276–283.
Pertiwi, M. V., Alfian, R., Nita, Y., & Athiyah, U. (2022). Medication adherence of diabetes mellitus patients in Indonesia: A systematic review. Pharmacy Education, 22(2), 188–193. https://doi.org/10.46542/pe.2022.222.188193
Pratiwi, F. I., & Widayati, A. (2021). Pengaruh Intervensi Tenaga Kesehatan terhadap Kepatuhan Minum Obat pada Pasien Diabetes Mellitus Tipe 2 di Indonesia: Kajian Literatur. Jurnal Sains Farmasi & Klinis, 8(2), 107. https://doi.org/10.25077/jsfk.8.2.107-115.2021
Putri, N. A., & Cholisoh, Z. (2023). Model Intervensi Kepatuhan Minum Obat Dan Kontrol Gula Darah Pada Pasien Diabetes Mellitus Tipe 2: Tinjauan Sistematis. JPP) Jurnal Kesehatan Poltekkes Palembang, 18(1), 103–114. https://doi.org/
Rasdianah, N., Martodiharjo, S., Andayani, T. M., & Hakim, L. (2020). Pengaruh Pelayanan Kefarmasian di Rumah pada Pasien Diabetes Melitus Tipe 2 di Puskesmas Wilayah Kota Yogyakarta. Journal of Management and Pharmacy Practice, 10(2), 126–136. https://doi.org/10.22146/jmpf.46240
Riskesdas. (2018). Laporan Nasional Riskesdas 2018. In Lembaga Penerbit Balitbangkes (pp. 1–627).
Rokhman, M. R., Darakay, C. N., & Raditya, R. (2015). Pengaruh Pemberian Home Care oleh Apoteker pada Pasien Diabetes Mellitus. Jurnal Manajemen Dan Pelayanan Farmasi, 5(3), 225–232.
Rony, D. Y., Sarnianto, P., & Anggriani, Y. (2020). Pengaruh Asuhan Kefarmasian Terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Puskesmas Kabupaten Cirebon. Jurnal Ilmiah Indonesia, 5(6), 64–77. https://core.ac.uk/download/pdf/235085111.pdf%250Awebsite: http://www.kemkes.go.id%250Ahttp://www.yankes.kemkes.go.id/assets/downloads/PMK No. 57 Tahun 2013 tentang PTRM.pdf%250Ahttps://www.kemenpppa.go.id/lib/uploads/list/15242-profil-anak-indonesia_-201
Sahin, C., Courtney, K. L., Naylor, P. J., & Rhodes, R. E. (2020). Patients’ Evaluations of Mobile Text Messaging Studies for Type 2 Diabetes Management: A Systematic Review and a Meta-Synthesis. Journal of Technology in Behavioral Science, 6(1). https://doi.org/10.1007/s41347-020-00168-1
Septiar, H. E., & Utami, P. (2015). Pengaruh Konseling Farmasis Terhadap Kualitas Hidup Dan Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2 Di Puskesmas Gedong Tengen Periode Maret-Mei 2014. FJurnal Farmasi Sains Dan Praktis, 1(1), 29–34. http://repository.umy.ac.id/handle/123456789/1989
Syarifuddin, S., Nasution, A., Dalimunthe, A., & Khairunnisa. (2019). Impact of pharmacist intervention on improving the quality of life of patients with type 2 diabetes mellitus. Open Access Macedonian Journal of Medical Sciences, 7(8), 1401–1405. https://doi.org/10.3889/oamjms.2019.140
Syifannisa, R., Muthoharoh, A., Ningrum, W. A., & Rahmatullah, S. (2022). Konseling Apoteker Meningkatkan Kepatuhan Pengobatan dan Menurunkan Kadar Gula Darah Pasien DM Tipe 2. Jurnal Ilmiah Kesehatan, 15(2), 93–102.
Tri Arsita Setyani, E., Anggraini, D., Ardyanti Aulia, R., & Wido Mukti, A. (2023). Artikel Review : Peranan Apoteker Dalam Pelayanan Kefarmasian Pada Pasien Diabetes Melitus (DM). FARMASIS: Jurnal Sains Farmasi, 4(2), 93–106.
Ariyani, H., Rahmani, & Hendera. (2022). Pengaruh Konseling Singkat Melalui Telepon Terhadap Penurunan Kadar Gula Darah Pasien Diabetes Melitus Di Puskesmas Alalak Selatan Kota Banjarmasin Utara. JCPS (Journal of Current Pharmaceutical Sciences), 5(2), 508–513.
Basuki, E. S. (2009). Konseling Medik : Kunci Menuju Kepatuhan Pasien. Majalah Kedokteran Indonesia, 59, 55–60.
Besemah, N. A., Sartika, R. A. D., & Sauriasari, R. (2021). Effect of Pharmacist Intervention on Medication Adherence and Clinical Outcomes of Type 2 Diabetes Mellitus Outpatients in Primary Healthcare in Indonesia. Journal of Research in Pharmacy Practice, 9(4), 186–195. https://doi.org/10.4103/jrpp.JRPP_20_59
Departemen Kesehatan Republik Indonesia. (2008). Riset Kesehatan Dasar 2007. In Laporan Nasional 2007. http://kesga.kemkes.go.id/images/pedoman/Riskesdas 2007 Nasional.pdf
Fajriansyah, Iskandarsyah, A., Puspitasari, I. M., & Lestari, K. (2020). Impact of pharmacist counseling on health-related quality of life of patients with type 2 diabetes mellitus: a cluster randomized controlled study. Journal of Diabetes and Metabolic Disorders, 19(2), 675–682. https://doi.org/10.1007/s40200-020-00528-x
Fitriana, Z., & Salviana, E. A. (2021). Analisis Faktor yang Mempengaruhi Kepatuhan Menjalankan Diet Pada Lansia Penderita Diabetes Melitus Tipe Dua. Jurnal Keperawatan Silampari, 4(2), 351–358.
Jannah, F., Safutra Suraya, A., Erindia, F., Nurwahidah, N., & Chayatush Sholichah, A. (2023). The Benefits of Telehealth on Quality of Life of People Living with Type 2 Diabetes Mellitus: A Literature Review. Fundamental and Management Nursing Journal, 6(2), 69–77. https://doi.org/10.20473/fmnj.v6i2.48692
Kementrian kesehatan republik indonesia. (2020). Tetap Produktif, Cegah Dan Atasi Diabetes Mellitus. In Pusat data dan informasi kementrian kesehatan RI.
Khairunnisa, Rawitri, K., Wiryanto, & Wahyuni, S. (2021). Pengaruh Asuhan Kefarmasian Terhadap Outcome Klinis Dan Kualitas Hidup Pada Pasien Diabetes Melitus Tipe 2. Jurnal Farmasi Indonesia, 13(2), 118–128. https://doi.org/10.35617/jfionline.v13i2.18
Laxmi, D., Kumala, S., Sarnianto, P., & Tarigan, A. (2021). Pengaruh Edukasi Farmasis Terhadap Hasil Terapi dan Kualitas Hidup Pasien Prolanis Diabetes Melitus Tipe 2. Jurnal Ilmiah Indonesia, 6(1), 154–172. http://www.nber.org/papers/w16019
Mayasari, Y., Sarnianto, P., & Anggraini, Y. (2020). Pengaruh Asuhan Kefarmasian Terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Dua Puskesmas Daerah Jakarta Timur. Jurnal Ilmiah Indonesia, 5(6), 221–232.
Octaviani, P. (2017). Pengaruh Pemberian Konseling Farmasis dengan Alat Bantu Terhadap Kepatuhan Pasien Diabetes Melitus Tipe 2 Anggota Prolanis di Puskesmas Purwokerto Utara. Viva Medika, 10(1), 68–78.
Partika, R., Angraini, D. I., & Fakhruddin, H. (2018). Pengaruh Konseling Gizi Dokter terhadap Peningkatan Kepatuhan Diet Pasien Diabetes Melitus Tipe 2. Majority, 7(3), 276–283.
Pertiwi, M. V., Alfian, R., Nita, Y., & Athiyah, U. (2022). Medication adherence of diabetes mellitus patients in Indonesia: A systematic review. Pharmacy Education, 22(2), 188–193. https://doi.org/10.46542/pe.2022.222.188193
Pratiwi, F. I., & Widayati, A. (2021). Pengaruh Intervensi Tenaga Kesehatan terhadap Kepatuhan Minum Obat pada Pasien Diabetes Mellitus Tipe 2 di Indonesia: Kajian Literatur. Jurnal Sains Farmasi & Klinis, 8(2), 107. https://doi.org/10.25077/jsfk.8.2.107-115.2021
Putri, N. A., & Cholisoh, Z. (2023). Model Intervensi Kepatuhan Minum Obat Dan Kontrol Gula Darah Pada Pasien Diabetes Mellitus Tipe 2: Tinjauan Sistematis. JPP) Jurnal Kesehatan Poltekkes Palembang, 18(1), 103–114. https://doi.org/
Rasdianah, N., Martodiharjo, S., Andayani, T. M., & Hakim, L. (2020). Pengaruh Pelayanan Kefarmasian di Rumah pada Pasien Diabetes Melitus Tipe 2 di Puskesmas Wilayah Kota Yogyakarta. Journal of Management and Pharmacy Practice, 10(2), 126–136. https://doi.org/10.22146/jmpf.46240
Riskesdas. (2018). Laporan Nasional Riskesdas 2018. In Lembaga Penerbit Balitbangkes (pp. 1–627).
Rokhman, M. R., Darakay, C. N., & Raditya, R. (2015). Pengaruh Pemberian Home Care oleh Apoteker pada Pasien Diabetes Mellitus. Jurnal Manajemen Dan Pelayanan Farmasi, 5(3), 225–232.
Rony, D. Y., Sarnianto, P., & Anggriani, Y. (2020). Pengaruh Asuhan Kefarmasian Terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Puskesmas Kabupaten Cirebon. Jurnal Ilmiah Indonesia, 5(6), 64–77. https://core.ac.uk/download/pdf/235085111.pdf%250Awebsite: http://www.kemkes.go.id%250Ahttp://www.yankes.kemkes.go.id/assets/downloads/PMK No. 57 Tahun 2013 tentang PTRM.pdf%250Ahttps://www.kemenpppa.go.id/lib/uploads/list/15242-profil-anak-indonesia_-201
Sahin, C., Courtney, K. L., Naylor, P. J., & Rhodes, R. E. (2020). Patients’ Evaluations of Mobile Text Messaging Studies for Type 2 Diabetes Management: A Systematic Review and a Meta-Synthesis. Journal of Technology in Behavioral Science, 6(1). https://doi.org/10.1007/s41347-020-00168-1
Septiar, H. E., & Utami, P. (2015). Pengaruh Konseling Farmasis Terhadap Kualitas Hidup Dan Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2 Di Puskesmas Gedong Tengen Periode Maret-Mei 2014. FJurnal Farmasi Sains Dan Praktis, 1(1), 29–34. http://repository.umy.ac.id/handle/123456789/1989
Syarifuddin, S., Nasution, A., Dalimunthe, A., & Khairunnisa. (2019). Impact of pharmacist intervention on improving the quality of life of patients with type 2 diabetes mellitus. Open Access Macedonian Journal of Medical Sciences, 7(8), 1401–1405. https://doi.org/10.3889/oamjms.2019.140
Syifannisa, R., Muthoharoh, A., Ningrum, W. A., & Rahmatullah, S. (2022). Konseling Apoteker Meningkatkan Kepatuhan Pengobatan dan Menurunkan Kadar Gula Darah Pasien DM Tipe 2. Jurnal Ilmiah Kesehatan, 15(2), 93–102.
Tri Arsita Setyani, E., Anggraini, D., Ardyanti Aulia, R., & Wido Mukti, A. (2023). Artikel Review : Peranan Apoteker Dalam Pelayanan Kefarmasian Pada Pasien Diabetes Melitus (DM). FARMASIS: Jurnal Sains Farmasi, 4(2), 93–106.
Published
2025-05-31
Section
Articles
.png)
1.png)
1.png){kind=small}
